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DNA Plays a Role in How People Experience the Effects of THC and CBD

Updated: Jul 29, 2023

THC (tetrahydrocannabinol) and CBD (cannabidiol) are Two of the Most Well-known Compounds Found in the Cannabis Plant


THC is the psychoactive compound that is responsible for the high associated with marijuana use, while CBD is a non-psychoactive compound that has been shown to have a variety of therapeutic benefits.



According to the National Institute of Health (NIH), a Person's DNA Plays a Role in How They May Experience the Effects of THC and CBD.


The NIH notes that the human body has a complex endocannabinoid system, which is involved in a variety of processes including pain, mood, and memory. This system includes cannabinoid receptors, which are found throughout the body and can be activated by THC and CBD.


A person's DNA May Affect Their Experience with THC and CBD Through Their Genetic Variations in the Cannabinoid Receptors.


Some people may have variations in their cannabinoid receptors that make them more sensitive to the effects of THC and CBD, while others may have variations that make them less sensitive. This can affect a person's response to these compounds and may explain why some people are more prone to experiencing the psychoactive effects of THC while others are more resistant to them.


Duration and Intensity of the Effects of THC and CBD Variations.


The liver is responsible for metabolizing these compounds, and certain genetic variations may affect how quickly or efficiently this process occurs. This can influence the duration and intensity of the effects of THC and CBD on a person.


A Person's DNA Plays a Role in How They Experience the Effects of THC and CBD.


While more research is needed to fully understand this relationship, it is important for individuals to be aware of their own unique genetic makeup and to consider this when using cannabis products. It is also important to note that the effects of THC and CBD can vary greatly from person to person and may be influenced by a variety of factors beyond genetics, such as the method of consumption, the dosage, and the individual's overall health and well-being.


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