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FAQ Chart: Human CBD Receptors

Updated: Oct 26, 2020

FAQ Chart: What are Human CBD Receptors?

What do CBD and receptors have to do with human health and wellness? While hemp and medical marijuana research is controversial, reports from Isreal to America are starting to reveal a very unique relationships with cannabis and the human body.

Have questions about medical cannabis, CBD, THC, and your health? Contact OMNI Medical Services today - ask about our telehealth options!

Chart: What is the Human CBD Receptor?

"phytocannabinoids, especially cannabidiol (CBD), have been suggested to exert beneficial effects in various pathological conditions, including inflammation, cancer, addiction and epilepsy."
Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System National Institute of Health

What is Cannabis?

The plant Cannabis sativa, aka marijuana, has been used for ceremonial and medical purpose throughout human history.

Documented uses of marijuana

In 1964, the world learned much more about marijuana with the discovery of Δ9-tetrahydrocannabinol (THC.)

THC is the main psychoactive component of approximately 70 phytocannabinoids identified in the plant.

This initial discovery led to the generation of a variety of synthetic cannabinoids with similar or distinct structures to phytocannabinoids.

  • led to the identification and successful cloning of the cannabinoid receptor 1 (CB1R)

  • cannabinoid receptor (CBR)

  • termed as the cannabinoid receptor 2 (CB2R)

  • CB1R and CB2R are widely-acknowledged as CBRs

More human receptors interact with cannabinoids

  • G protein-coupled receptors (GPCRs)

  • ion channels

  • nuclear receptors

Other receptors serve as endogenous agonists of CBRs endocannabinoids

  • N-arachidonoyl-ethanolamine (AEA; anandamide)

  • 2-arachidonoylglycerol (2-AG)

"In recent years, much attention has been drawn to utilizing marijuana extracts in medicine [14]. Due to the clinical application of marijuana and the non-psychoactive nature of most phytocannabinoids except THC, the therapeutic potential of these compounds has been greatly appreciated."
Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System National Institute of Health

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